How to perform mouse move event on cross domain frames in a page and read data related to that element?

I am trying to read content from the frame in chrome extension. I am able to perform ‘mouseover’ event inside frame if the frame is of the same domain as that of the page. I have followed below approach to perform mouseover event on elements inside a frame of the same domain.

function FrameMousemove(iframe) {
     iframe.contentWindow.addEventListener('mousemove', function (event) {
         alert(event.srcElement.innerHTML);
     });
};

FrameMousemove(document.getElementById("IF1"));

By using this code when I move the mouse onto any element inside frame an alert is displaying with innerHTML of mouse hovered element. I want similar functionality for cross-domain frames. Is that possible? If not can anyone let me know why?